B-Tg(mMmp8) MC38
|
Common name |
B-Tg(mMmp8) MC38 | Catalog number | 321892 |
| Aliases |
BB138268 |
Disease | Colon carcinoma |
|
Organism |
Mouse |
Strain | C57BL/6 |
| Tissue types | Colon | Tissue | Colon |
The exogenous promoter and mouse Mmp8 coding sequence were inserted into the mouse genome randomly. Mouse Mmp8 is highly expressed on the surface of B-Tg(mMmp8) MC38 cells.
Subcutaneous homograft tumor growth of B-Tg(mMmp8) MC38 cells. B-Tg(mMmp8) MC38 cells (5x105) and wild-type MC38 cells (5x105) were subcutaneously implanted into C57BL/6 mice (female, 7-week-old, n=6). Tumor volume and body weight were measured twice a week. (A) Average tumor volume ± SEM. (B) Body weight (Mean± SEM). Volume was expressed in mm3 using the formula: V=0.5 X long diameter X short diameter2. As shown in panel A, B-Tg(mMmp8) MC38 cells were able to establish tumors in vivo and can be used for efficacy studies.
B-Tg(mMmp8) MC38 tumor cells growth of individual mice. B-Tg(mMmp8) MC38 cells (5x105) and wild-type MC38 cells (5x105) were subcutaneously implanted into C57BL/6 mice (female, 7-week-old, n=6). As shown in panel, B-Tg(mMmp8) MC38 cells were able to establish tumors in vivo and can be used for efficacy studies.
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