|Strain Name||C57BL/6-Angptl8tm1(ANGPTL8)/Bcgen||Common Name||B-hANGPTL8 mice|
||ANGPTL8, angiopoietin like 8, C19orf80, PRO1185, PVPA599, RIFL, TD26|
NCBI Gene ID
mRNA expression analysis
Strain specific analysis of ANGPTL8 gene expression in wild-type mice and B-hANGPTL8 mice by RT-PCR. Mouse Angptl8 mRNA was detectable in the wild-type mice (+/+). Human ANGPTL8 mRNA was detectable only in homozygous B-hANGPTL8 mice but not in wild-type mice.
Protein expression analysis
Strain specific ANGPTL8 expression analysis in homozygous B-hANGPTL8 mice by ELISA.
Plasma was collected from wild-type mice (+/+) and homozygous B-hANGPTL8 mice (H/H), and analyzed by ELISA. ANGPTL8 was both detectable in wild-type mice and B-hANGPTL8 mice (H/H) due to the cross-reactivity of ELISA kit.