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B-hALB mice
Strain Name C57BL/6-Albtm1(ALB)/Bcgen Common Name  B-hALB mice
Background C57BL/6 Catalog number  110960
Related Genes 
Albumin, Al; Alb1; Alb-1; BCL002

Gene description

Albumin is a family of globular proteins, the most common of which are the serum albumins. It is the most abundant protein in human blood plasma; it constitutes about half of serum protein. It is produced in the liver. It is soluble in water, and it is monomeric. Albumin is a natural transport protein with multiple ligand binding sites, cellular receptor engagement, and a long circulatory half-life due to interaction with the recycling neonatal Fc receptor. Albumins in general are transport proteins that bind to various ligands and carry them around. It has long been the center of attention in the pharmaceutical industry due to their ability to bind to various drug molecules, great stability during storage and in vivo usage, no toxicity and antigenicity, biodegradability, reproducibility, scale up of the production process and a better control over release properties. 

Protein expression analysis 


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Strain specific ALB expression analysis in heterozygous B-hALB mice by ELISA. 
Serum was collected from C57BL/6 wild-type mice (+/+) and heterozygous B-hALB mice (H/+) analyzed by ELISA with species-specific ALB ELISA kit. Mouse ALB were both detectable in wild-type mice and heterozygous B-hALB mice. Human ALB was exclusively detectable in heterozygous B-hALB mice but not in wild-type mice. ND: not detected.