|Strain Name||C57BL/6-Cd63tm1(CD63)/Bcgen||Common Name||B-hCD63 mice|
|Aliases||CD63(CD63 molecule), LAMP-3, ME491, MLA1, OMA81H, TSPAN30|
CD63 (gene ID 967), also known as LAMP-3 or ME491 (melanoma-associated antigen), MLA1, OMA81H, TSPAN30, encodes a cell surface glycoprotein. CD63 is a member of the tetraspan transmembrane superfamily (TM4SF) protein expressed on activated platelets, monocytes/macrophages, endothelium, fibroblasts, osteoclasts, and smooth muscle cells.CD63 functions as cell surface receptor for TIMP1 and has functions in mediating signal transduction processes and then regulate a variety of cellular processes such as cell proliferation, activation and motility. It has been reported that CD63 protein associated with tumor progression and served as a blood platelet activation marker and the deficiency of this protein may be associated with Hermansky-Pudlak syndrome (HPS).
mRNA expression analysis
Protein expression analysis