Strain Name |
C57BL/6JNifdc-Adamts13tm1Bcgen/Bcgen |
Common Name |
B-Adamts13 KO mice |
Background | C57BL/6JNifdc | Catalog number |
113720 |
Related Genes |
ADAM-TS13, ADAMTS-13, C9orf8, VWFCP, vWF-CP |
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NCBI Gene ID |
11093 |
Description
Targeting strategy
Gene targeting strategy for B-Adamts13 KO mice. The exons 1-23 of mouse Adamts13 gene were knocked out in B-Adamts13 KO mice.
mRNA expression analysis
Strain specific analysis of Adamts13 mRNA expression in wild-type C57BL/6 mice and B-Adamts13 KO mice by RT-PCR. Liver RNA were isolated from wild-type C57BL/6 mice (+/+) and homozygous B-Adamts13 KO mice (-/-), then cDNA libraries were synthesized by reverse transcription, followed by PCR with mouse Adamts13 primers. Mouse Adamts13 mRNA were detectable only in wild-type C57BL/6 mice but not in homozygous B-Adamts13 KO mice.