||B-hPD-L2 MC38||Catalog number||310703|
|Aliases||PDCD1LG2, CD273, PDCD1L2||Disease||Colon carcinoma|
The mouse PD-L2 gene was replaced by human PD-L2 coding sequence in B-hPD-L2 MC38 cells. Human PD-L2 is highly expressed on the surface of B-hPD-L2 MC38 cells.
Subcutaneous homograft tumor growth of B-hPD-L2 MC38 cells. B-hPD-L2 MC38 cells (5x105) were subcutaneously implanted into C57BL/6 mice (female, 5-8-week-old, n=5). Tumor volume and body weight were measured twice a week. (A) Average tumor volume ± SEM. (B) Body weight (Mean± SEM). Volume was expressed in mm3 using the formula: V=0.5 X long diameter X short diameter2. As shown in panel A, B-hPD-L2 MC38 cells were able to establish tumors in vivo and can be used for efficacy studies.