百奥赛图将出席于2023年11月1-5日在美国圣地亚哥举办的第38届癌症免疫治疗学会年会(SITC)。期间将展示16张海报,包括9张新药资产海报和7张基因编辑动物模型海报;并设立展台223。
欢迎在海报及展台与我们的团队见面,了解我们在抗体新药研发及临床前动物模型和服务(BioMice)方面的最新进展。无论您对我们货架型新药资产、全人抗体/TCR发现平台、货架型动物/细胞模型、还是药理药效服务感兴趣,我们都期待与您洽谈合作,支持您的研发需求。
海报展示:
双抗ADC药物资产
DM001: A novel bispecific ADC targeting TROP2 and EGFR with potent anti-tumor efficacy in PDX models
海报编号: 1152
展出时间: November 4th, 2023
Preclinical evaluation of fully human bispecific antibody-drug candidates targeting HER3 and the juxtamembrane region of MUC1
海报编号: 1165
展出时间: November 3rd, 2023
DM005, an EGFR х MET bispecific antibody-drug conjugate, showed robust anti-tumor activity in PDX models
海报编号: 1150
展出时间: November 4th, 2023
BSA01, a bispecific antibody-drug conjugate targeting EGFR and membrane-bound MUC-1-C, exhibits anti-tumor efficacy in vivo
海报编号: 1164
展出时间: November 4th, 2023
BCG022: A HER3×MET bispecific antibody-drug conjugate (BsADC) targeting key mechanisms of bypass resistance in multiple tumor types
海报编号: 1153
展出时间: November 3rd, 2023
A novel bispecific antibody-drug conjugate targeting PTK7 and TROP2, BCG033, demonstrates preclinical efficacy against triple-negative breast cancer xenografts
海报编号: 1163
展出时间: November 3rd, 2023
类TCR抗体新药资产
Identification of fully human TCR-mimic antibodies targeting the KRAS G12V/HLA complex generated in HLA-transgenic RenMabTM mice
海报编号: 1168
展出时间: November 4th, 2023
Preclinical application of a fully human TCR-mimic antibody developed to target NY-ESO-1/HLA-A02
海报编号: 356
展出时间: November 4th, 2023
全人单抗药物资产
Fc-competent fully human anti-TIGIT blocking monoclonal antibodies demonstrated potent anti-tumor efficacy in preclinical models
海报编号: 479
展出时间: November 3rd, 2023
靶点人源化小鼠模型
Development of a preclinical CD98HC mouse model for therapeutic studies
海报编号: 13
展出时间: November 3rd, 2023
Generation and validation of humanized GARP/TGFB1 mice for testing novel anti-human GARP antibodies
海报编号: 18
展出时间: November 4th, 2023
Humanized CD200/CD200R mice as a tool for evaluating novel therapeutics
海报编号: 12
展出时间: November 4th, 2023
Humanized ICOS mice as a novel tool for predicting and monitoring T-cell-mediated immunotherapy response
海报编号: 11
展出时间: November 3rd, 2023
Humanized NKP46 mouse models for testing novel NK cell-based immunotherapies
海报编号: 17
展出时间: November 3rd, 2023
Preclinical CD3-based mouse models for evaluation of bi-specific T-cell engager antibodies
海报编号: 19
展出时间: November 3rd, 2023
免疫缺陷小鼠模型
A novel B2m-deficient immunodeficient model expressing human IL-15 for preclinical evaluation of T cell and NK cell-based therapies
海报编号: 16
展出时间: November 4th, 2023
关于百奥赛图
百奥赛图(股票代码:02315.HK)是一家创新技术驱动新药研发的国际性生物技术公司,致力于成为全球新药发源地,以专注技术创新、持续新药产出、守护人类健康为使命。基于百奥赛图自主研发并拥有完全独立知识产权的全人抗体RenMice®平台(RenMab®、RenLite®和RenNano®小鼠),将单抗、双抗和纳米抗体开发技术平台、动物体内药效筛选平台、强大的临床开发能力有机整合在一起,形成了独具特色、涵盖药物研发全流程的新药研发能力。百奥赛图正在对1000多个潜在可成药的靶点进行规模化药物开发(“千鼠万抗TM”计划),截至2023年6月30日,百奥赛图已签署了50项药物合作开发/授权/转让协议并与包括多家MNC在内的企业达成了42个靶点项目RenMice®平台授权开发合作。 同时百奥赛图建立了由10项在研药物组成的核心管线,并且我们已就其中多项临床资产与外部合作方建立了项目合作关系。未来,百奥赛图将继续携手全球合作伙伴,持续产出众多抗体药物,更好地惠及患者。百奥赛图总部位于北京,在中国(江苏海门、上海)、美国(波士顿、旧金山)及德国海德堡等地设有分支机构。欲了解更多信息,请访问官网https://www.biocytogen.com.cn/。
百奥赛图联系人
抗体新药研发:BD-Licensing@biocytogen.com
BioMice:info@bbctg.com.cn