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模型资源
动物/细胞资源
免疫缺陷鼠
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动物/细胞资源
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肿瘤类
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慢性肾病(CKD)模型
炎症和自免类
类风湿性关节炎(RA)疾病模型
特应性皮炎(AD)模型
肺纤维化模型
系统性红斑狼疮(SLE)模型
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骨质疏松小鼠模型
迟发性超敏反应(DTH)疾病模型
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多发性硬化(MS)模型
炎症性肠病( IBD)模型
B-NDG系列免疫缺陷小鼠
产品编号
常规命名
应用领域
110586
B-NDG mice
Immune reconstitution, CDX, transplantation, drug evaluation
110586
B-NDG mice-PDX
Immune reconstitution, CDX, transplantation, drug evaluation
110587
B-NDG nude mice
Human immune system reconstitution
110601
B-NDG B2m KO mice plus
Reduce PBMC reconstitution GVHD response and prolong experimental window
110600
B-NDG hIL15 mice
Promote human NK cell differentiation
110599
B-NDG HLA-A2.1 mice
Vaccine study
110596
B-NDG hIL6 mice
Promotes human monocyte differentiation
110590
B-NDG hTHPO mice
Without irradiation, it reduces the damage caused by irradiation to mice
110604
B-NDG hSIRPA mice
Maintain progenitor capacity
120612
B-NDG hIL7/hIL15 mice
Promote differentiation of human T cells and NK cells
110603
B-NDG hSIRPA/hCD47 mice
Evaluation of pharmacodynamic and toxicity of CD47, SIRPA targeted drugs
120609
B-NDG hCSF1/hTHPO mice
Promote differentiation of human myeloid cells without irradiation
113231
B-NDG hGPC3 mice
113220
B-NDG hHER3 mice
112704
B-NDG MHC I/II DKO/hMSLN mice
113178
B-NDG hTROP2 mice
112839
B-NDG FcγR KO mice
113801
B-NDG hTHPO/hSCF mice
110591
B-NDG hCSF1 mice
112869
B-NDG Flt3 KO mice
This product results in a high level of immune system reconstitution after the transplantation of hematopoietic stem cells, especially for DC cells.
112889
B-NDG hFLT3LG, Flt3 KO mice
113385
B-NDG hIL2 mice
112863
huHSC-B-NDG hCSF1/hTHPO mice
112484
huPBMC-B-NDG B2m KO mice plus
112474
B-NDG hB2M/HLA-A11.1 mice plus
112590
B-NDG Tg(RORγt-Il2rg) mice
112914
B-NDG Kit W41 mice
112874
B-NDG hB2M/HLA-A24.2 mice plus
112873
B-NDG hB2M/HLA-A3.1 mice plus
112774
B-NDG hALB/hFcRn mice
112864
huHSC-B-NDG hIL6 mice
Promote differentiation of human monocyte-macrophage
112480
huHSC-B-NDG hTHPO mice
Irradiation is not required to avoid damage to mice caused by irradiation
112479
huHSC-B-NDG MGMT3 mice
Promote differentiation of human myeloid cells;Irradiation is not required to avoid damage to mice caused by irradiation
112865
huHSC-B-NDG HLA-A2.1 mice
To verify the efficacy of HLA-A2.1 restricted vaccines;Promote the development of human CD8+ T cells
112451
B-NDG hB2M/HLA-A11.1 mice
To verify the efficacy of HLA-A11.1 restricted vaccines and antibody-based therapies;Promote the development of human CD8+ T cells
112560
B-NDG hB2M/HLA-A24.2 mice
To verify the efficacy of HLA-A24.2 restricted vaccines and antibody-based therapies;Promote the development of human CD8+ T cells
112450
B-NDG hB2M/HLA-A3.1 mice
To verify the efficacy of HLA-A3.1 restricted vaccines and antibody-based therapies;Promote the development of human CD8+ T cells
112256
B-NDG H2-K1/H2-D1 KO mice
No MHC class I molecule expression; Reduce GVHD and prolong the experimental window period; Improve the accuracy of efficacy verification
111982
B-NDG hALB mice
Used for pharmacological or pharmacokinetic studies of drugs that utilize albumin to extend their half-life
112653
B-NDG hIL15, FcγR KO mice
Promote differentiation of human NK cells;No mouse Fc receptor function
112478
huHSC-B-NDG hIL15 mice
Promote differentiation of human NK cells
112482
huNK-B-NDG hIL15 mice
Promote differentiation of human NK cells
112449
B-NDG hB2M/HLA-A2.1 mice plus
To verify the efficacy of HLA-A2.1 restricted vaccines and antibody-based therapies;Promote the development of human CD8+ T cells
112470
huHSC-B-NDG mice
Human immune system reconstitution, mainly T cells and B cells;reconstitutionl Human-derived cell or tissue engraftmentl Tumor research;Human disease model studyl Efficacy and toxicity verification for
112469
huPBMC-B-NDG mice
Human T cell reconstitution;Human-derived cell or tissue engraftment;Tumor researchl Human disease model study;Efficacy and toxicity verification for human targeted drugs
110593
B-NDG hGM-CSF mice
Promote differentiation of human myeloid cells;For mating with other humanized mice that promote myeloid cell differentiation to obtain multi-humanized mice
110598
B-NDG hairless mice
Hairless, easy to measure tumor
110597
B-NDG hIL7 mice
Promote differentiation of human lymphoid cells
110595
B-NDG H2-Ab1 KO mice
No MHC class II molecule expression; Reduce GVHD and prolong the experimental window period;Improve the accuracy of efficacy verification
111882
B-NDG MGMT3 mice
Promote differentiation of human myeloid cells;Irradiation is not required to avoid damage to mice caused by irradiatio
111895
B-NDG MHC I/II DKO mice plus
No MHC class I/II molecule expression;Reduce GVHD and prolong the experimental window period;Improve the accuracy of efficacy verification
111922
B-NDG hFcRn mice
PK (NDG background can reduce ADA)
111856
B-NDG B2m plus/hIL15 mice
Human immune system reconstitution
110605
B-NDG Hc mice
Antibody CDC function study
产品编号
常规命名
应用领域
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立足全球生物医药行业,从技术创新出发,百奥赛图建立“BioMice百奥动物”子品牌。百奥动物集创新动物模型研发制备、生产供应和实验服务为一体,拥有2800余个独特基因编辑动物/细胞系模型,覆盖肿瘤,自免,代谢等多个疾病领域。创新的动物模型、高标准的质量管理、多元化的服务平台,助推生物医药创新产业的快速发展。
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