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B-NDG系列免疫缺陷小鼠
产品编号 常规命名 应用领域
110586 B-NDG mice Immune reconstitution, CDX, transplantation, drug evaluation
110586 B-NDG mice-PDX Immune reconstitution, CDX, transplantation, drug evaluation
110587 B-NDG nude mice Human immune system reconstitution
110601 B-NDG B2m KO mice plus Reduce PBMC reconstitution GVHD response and prolong experimental window
110600 B-NDG hIL15 mice Promote human NK cell differentiation
110599 B-NDG HLA-A2.1 mice Vaccine study
110596 B-NDG hIL6 mice Promotes human monocyte differentiation
110590 B-NDG hTHPO mice Without irradiation, it reduces the damage caused by irradiation to mice
110604 B-NDG hSIRPA mice Maintain progenitor capacity
120612 B-NDG hIL7/hIL15 mice Promote differentiation of human T cells and NK cells
110603 B-NDG hSIRPA/hCD47 mice Evaluation of pharmacodynamic and toxicity of CD47, SIRPA targeted drugs
120609 B-NDG hCSF1/hTHPO mice Promote differentiation of human myeloid cells without irradiation
112889 B-NDG hFLT3LG, Flt3 KO mice
113385 B-NDG hIL2 mice
112863 huHSC-B-NDG hCSF1/hTHPO mice
112484 huPBMC-B-NDG B2m KO mice plus
112474 B-NDG hB2M/HLA-A11.1 mice plus
112590 B-NDG Tg(RORγt-Il2rg) mice
112914 B-NDG Kit W41 mice
112874 B-NDG hB2M/HLA-A24.2 mice plus
112873 B-NDG hB2M/HLA-A3.1 mice plus
112774 B-NDG hALB/hFcRn mice
112864 huHSC-B-NDG hIL6 mice Promote differentiation of human monocyte-macrophage
112480 huHSC-B-NDG hTHPO mice Irradiation is not required to avoid damage to mice caused by irradiation
112479 huHSC-B-NDG MGMT3 mice Promote differentiation of human myeloid cells;Irradiation is not required to avoid damage to mice caused by irradiation
112865 huHSC-B-NDG HLA-A2.1 mice To verify the efficacy of HLA-A2.1 restricted vaccines;Promote the development of human CD8+ T cells
112451 B-NDG hB2M/HLA-A11.1 mice To verify the efficacy of HLA-A11.1 restricted vaccines and antibody-based therapies;Promote the development of human CD8+ T cells
112560 B-NDG hB2M/HLA-A24.2 mice To verify the efficacy of HLA-A24.2 restricted vaccines and antibody-based therapies;Promote the development of human CD8+ T cells
112450 B-NDG hB2M/HLA-A3.1 mice To verify the efficacy of HLA-A3.1 restricted vaccines and antibody-based therapies;Promote the development of human CD8+ T cells
112256 B-NDG H2-K1/H2-D1 KO mice No MHC class I molecule expression; Reduce GVHD and prolong the experimental window period; Improve the accuracy of efficacy verification
111982 B-NDG hALB mice Used for pharmacological or pharmacokinetic studies of drugs that utilize albumin to extend their half-life
112653 B-NDG hIL15, FcγR KO mice Promote differentiation of human NK cells;No mouse Fc receptor function
112478 huHSC-B-NDG hIL15 mice Promote differentiation of human NK cells
112482 huNK-B-NDG hIL15 mice Promote differentiation of human NK cells
112449 B-NDG hB2M/HLA-A2.1 mice plus To verify the efficacy of HLA-A2.1 restricted vaccines and antibody-based therapies;Promote the development of human CD8+ T cells
112470 huHSC-B-NDG mice Human immune system reconstitution, mainly T cells and B cells;reconstitutionl Human-derived cell or tissue engraftmentl Tumor research;Human disease model studyl Efficacy and toxicity verification for
112469 huPBMC-B-NDG mice Human T cell reconstitution;Human-derived cell or tissue engraftment;Tumor researchl Human disease model study;Efficacy and toxicity verification for human targeted drugs
110593 B-NDG hGM-CSF mice Promote differentiation of human myeloid cells;For mating with other humanized mice that promote myeloid cell differentiation to obtain multi-humanized mice
110598 B-NDG hairless mice Hairless, easy to measure tumor
110597 B-NDG hIL7 mice Promote differentiation of human lymphoid cells
110595 B-NDG H2-Ab1 KO mice No MHC class II molecule expression; Reduce GVHD and prolong the experimental window period;Improve the accuracy of efficacy verification
111882 B-NDG MGMT3 mice Promote differentiation of human myeloid cells;Irradiation is not required to avoid damage to mice caused by irradiatio
111895 B-NDG MHC I/II DKO mice plus No MHC class I/II molecule expression;Reduce GVHD and prolong the experimental window period;Improve the accuracy of efficacy verification
111922 B-NDG hFcRn mice PK (NDG background can reduce ADA)
111856 B-NDG B2m plus/hIL15 mice Human immune system reconstitution
110605 B-NDG Hc mice Antibody CDC function study
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